Aktualności z naszego Twittera

It feels special to see that my former Master student @TomaszWypych8 is now a PI himself! Big thanks for the warm welcome @NenckiInstitute and for the opportunity to share our latest findings on #MultipleSclerosis #COVID19 and #LongCovid.

📣We are #hiring!

Position: 𝐏𝐨𝐬𝐭𝐝𝐨𝐜𝐭𝐨𝐫𝐚𝐥 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫 at Laboratory of Neuroinformatics

Field of science:  Neurophysiology

OPUS21 “Integration of sensory and cortical input in the generation of ketamine-dependent high-frequency oscillations in rodents.”

Yesterday #PolSCA @PAN_akademia held the very 1st meeting of its #AdvisoryCouncil for 2023-2026

Glad to inform that Prof. Leszek Kaczmarek of the @BRAINCITYWarsaw @NenckiInstitute has been chosen as its Chairman👏

Meet the Council, that we will have privilege to work with⤵️

CEL

Czym jest
BRAINCITY i
jaki był cel powstania centrum?

Celem BRAINCITY jest pogłębienie wiedzy na temat plastyczności neuronalnej i synaptycznej w celu zwalczania najbardziej wyniszczających i kosztownych chorób dotykających ludzi.

Brain plasticity refers to the capacity of structural and functional reorganization of the neuronal network in response to environmental challenges. Beside learning and memory which allow for adaptation to the changing environment, neuroplasticity is necessary to recover after disorders and injuries. Brain plasticity is manifested at many levels in the nervous system, ranging from molecular events, such as changes in gene expression, to behavior. At the cellular level, the plasticity is supported by dynamic modifications in neuronal connectivity and excitability that are driven by molecular changes in neurons and glial cells. Synapses are particularly prone to dynamic alterations and thus believed to play a major role in the plasticity. The BRAINCITY laboratories will study in state-of–the-art and highly complementary manner neural plasticity-dependent remodeling of the brain circuitry, whose abnormalities have recently been recognized as fundamental underpinnings of neuronal and psychiatric disorders (e.g. epilepsy, schizophrenia,

addiction, depression, and autism spectrum disorders). The studies will cover a range of research questions and approaches from synaptic plasticity and its molecular mechanisms, to imaging, visualization and manipulation of the brain-wide neuronal networks. Our aim is to identify novel diagnostic and therapeutic targets and thus stimulate the development of new therapies. The attractive novelty and importance proposed by the BRAINCITY is in its close collaborations of multidisciplinary research with clinics that will sharpen the focus on relevant molecular mechanisms, while collaborations with companies will help to address market needs and opportunities. Topics of particular interest for BRAINCITY include genomics and epigenomics, clinical neuroscience, circuitry, neurodevelopment, and disease modeling studied by such experimental approaches as iPSC-derived brain organoids, bioimaging, in vivo and in vitro gene editing, bioinformatics, high-content behavioral assessment, and drug screening.

Współpraca

Działalność BRAINCITY opiera się na strategicznej długofalowej współpracy Instytutu Biologii Doświadczalnej im. M. Nenckiego z EMBL – organizacją, która jest światowym liderem w badaniach naukowych, szkoleniach i transferze technologii.

BRAINCITY i Europejskie Laboratorium Biologii Molekularnej (EMBL) nawiązały długofalową, strategiczną współpracę. Strategiczne partnerstwo z EMBL opiera się na współpracy z wiodącymi instytucjami naukowymi w państwach członkowskich EMBL, wspólnie tworząc międzynarodową sieć ośrodków doskonałości naukowej, wraz z dostępnością zaawansowanych szkoleń EMBL. W szczególności, EMBL wspiera BRAINCITY w zakresie transferu wiedzy z zakresu neuronauki, kultury badawczej oraz nowoczesnego podejścia do zarządzania, w tym regularnej ewaluacji i internacjonalizacji niezależnych grup badawczych i wspierania praktyk transferu technologii.


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